The Problem
Neuroma pain is a critical issue for amputees.
Neuroma pain is a critical issue for amputees.
Neuroma pain is a critical issue for amputees.
Major peripheral nerve injuries, like those that result in amputation, frequently result in disorganized nerve tumors known as neuromas. Left untreated, they result in chronic, debilitating pain. Existing treatments are either insufficient or completely neglect nerve regeneration.
TMR has a size mismatch failure.
Neuroma pain is a critical issue for amputees.
Neuroma pain is a critical issue for amputees.
Targeted muscle reinnervation (TMR), which provides a reinnervation target for the nerve stump, is a promising surgical approach for neuroma management. However, a significant failure rate remains due to inherent size mismatch between the stump and the motor nerve target.
The Innerva Conduit.
Simple. Pain-Relieving. Transformative.
Through an elegant materials and structural design, our device mechanically and chemically facilitates tapered nerve growth to address size mismatch and simplifies TMR.
Our Team
Hai-Quan Mao, PhD
Hai-Quan Mao, PhD
Hai-Quan Mao, PhD
- Associate Director, Institute of NanoBioTechnology (INBT)
- Professor, Department of Materials Science & Engineering and Department of Biomedical Engineering, Johns Hopkins University
Sami Tuffaha, MD
Hai-Quan Mao, PhD
Hai-Quan Mao, PhD
- Assistant Professor, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine
Anson Zhou
Hai-Quan Mao, PhD
Bruce Enzmann
- Department of Biomedical Engineering, Johns Hopkins University ('23)
Bruce Enzmann
Bruce Enzmann
Bruce Enzmann
- Department of Materials Science & Engineering, Johns Hopkins University ('22)
Michael Lan
Bruce Enzmann
Erica Lee, MS
- Department of Biomedical Engineering, Johns Hopkins University ('21)
- NYU Grossman School of Medicine ('25)
Erica Lee, MS
Bruce Enzmann
Erica Lee, MS
- Department of Neuroscience, Johns Hopkins University ('17, '18)
- Johns Hopkins University School of Medicine ('22)
Juan Diego Carrizo
Juan Diego Carrizo
Juan Diego Carrizo
- Department of Materials Science & Engineering, Johns Hopkins University ('23)